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Home > USMLE > USMLE Certifications > USMLE-STEP-1
USMLE USMLE-STEP-1  Exam Questions & Answers
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USMLE USMLE-STEP-1 Exam Questions & Answers


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  • Vendor: USMLE

    Exam Code: USMLE-STEP-1

    Exam Name: United States Medical Licensing Step 1

    Certification Provider: USMLE

    Total Questions: 847 Q&A ( View Details)

    Updated on: Jul 05, 2026

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Related Exams

  • USMLE-STEP-1 United States Medical Licensing Step 1
  • USMLE-STEP-2 United States Medical Licensing Step 2
  • USMLE-STEP-3 United States Medical Licensing Step 3

Related Certifications

  • USMLE Certifications

USMLE-STEP-1 Online Practice Questions and Answers

Questions 1

A patient has been admitted for hematemesis (vomiting of blood). Endoscopic examination reveals bleeding esophageal varices resulting from portal obstruction. These varices represent anastomoses between branches of which of the following?

A. inferior vena cava with a patent ductus venosus

B. left gastric, azygos, and hemiazygos veins

C. right gastric vein and the inferior vena cava

D. superior, middle, and inferior rectal veins

E. veins running on the ligamentum teres and the epigastric veins

Show Answer

Correct Answer: B

Section: Anatomy Obstruction of the portal vein results in an increase in the collateral circulation between veins that normally drain to the portal vein and those that drain to the systemic veins. Choices A, B, D, and E all represent possible collateral venous circulation in case of portal obstruction. Choice Ais rare because the ductus venosus closes after birth. Choice B is correct because varicose veins in this region give rise to esophageal varices. Choice D results in varicose veins in the rectal region. Choice C is incorrect because there is no connection between the right gastric vein and the inferior vena cava. In choice E, enlargement of the epigastric veins results in varicose veins radiating from the umbilicus, the caput medusae.

Questions 2

A 15-year-old high school football player is brought to the emergency room. On examination, his right lower limb is deformed and swollen around the knee. At full extension, there is valgus instability, suggestive of knee dislocation. The patient is in great pain and there is a concern for concomitant vascular and nervous injuries. Palpation of the dorsalis pedis artery reveals a normal pulse. However, neurological examination reveals impaired dorsiflexion of the foot with decreased sensation in the space between digits 1 and 2. Which of the following nerves is affected?

A. deep peroneal (fibular) nerve

B. femoral nerve

C. saphenous nerve

D. superficial peroneal (fibular) nerve

E. tibial nerve

Show Answer

Correct Answer: A

Section: Anatomy The deep peroneal (fibular) nerve innervates the muscles responsible for dorsiflexion in the anterior compartment of the leg. It also provides for the cutaneous innervation of the space between digits 1 and

2. The femoral nerve (choice B) innervates muscles in the anterior compartment of the thigh and the skin of the medial aspect of the leg by a continuing branch, the saphenous nerve (choice C). The superficial peroneal (fibular) nerve (choice D) innervates the lateral compartment of the leg and muscles responsible for foot eversion. The tibial nerve (choice E) innervates the posterior compartment of the leg and the muscles responsible for plantar flexion.

Questions 3

Which of the following quantitative comparisons of haloperidol (H) and olanzapine (O) is most accurate?

A. Option A

B. Option B

C. Option C

D. Option D

E. Option E

Show Answer More Questions

Correct Answer: B

Section: Pharmacology Haloperidol is an older oral and parenteral antipsychotic drug with high extrapyramidal but low autonomic toxicity. Olanzapine is a new oral antipsychotic agent with low extrapyramidal and autonomic activity.

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